An inherited disorder characterized by a lack of the alpha-1 antitrypsin protease inhibitor. Alpha-1 antitrypsin deficiency leads to damage of various organs, especially the lung and liver. Symptoms may become apparent at a very early age or anytime later, manifesting as shortness of breath due to emphysema or as liver symptoms such as jaundice, fa [..]

A genetic disorder caused by low levels of alpha-1 antitrypsin, a protein that protects the lungs. Alpha-1 antitrypsin deficiency (A1AD) puts a person at risk of developing emphysema or chronic obstru [..]

<respiratory medicine> Deficiency of the protease inhibitor alpha-1 antitrypsin, leads primarily to degradation of elastin of the alveolar walls, as well as other structural proteins of a variety of tissues. The lack of this protein leads to damage of various organs, but mainly to the lung and liver. symptoms may become apparent at a very ear [..]

A inherited disease characterized by reduced levels or the absence of AAT in the blood and tissues that results in lung and liver disease.